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<p>Contributors ix</p> <p>Preface xiii</p> <p>Important Notice xv</p> <p>Abbreviations xvii</p> <p><b>Section I General Principles of Antimicrobial Therapy 1</b></p> <p>1 Antimicrobial Drug Action and Interaction: An Introduction 3<br /><i>Steeve Giguère</i></p> <p>2 Antimicrobial Susceptibility Testing Methods and Interpretation of Results 11<br /><i>Joseph E. Rubin</i></p> <p>3 Antimicrobial Resistance and its Epidemiology 21<br /><i>Patrick Boerlin and David G. White</i></p> <p>4 Principles of Antimicrobial Drug Bioavailability and Disposition 41</p> <p><i>J. Desmond Baggot and Steeve Giguère</i></p> <p>5 The Pharmacodynamics of Antimicrobial Agents 79<br /><i>Marilyn N. Martinez, Pierre-Louis Toutain, and John Turnidge</i></p> <p>6 Principles of Antimicrobial Drug Selection and Use 105<br /><i>Steeve Giguère</i></p> <p>7 Antimicrobial Stewardship in Animals 117<br /><i>J. Scott Weese, Stephen W. Page, and John F. Prescott</i></p> <p><b>Section II Classes of Antimicrobial Agents 133</b></p> <p>8 Beta-lactam Antibiotics: Penam Penicillins 135<br /><i>John F. Prescott</i></p> <p>9 Beta-lactam Antibiotics: Cephalosporins 153<br /><i>John F. Prescott</i></p> <p>10 Other Beta-lactam Antibiotics: Beta-lactamase Inhibitors, Carbapenems, and Monobactams 175<br /><i>John F. Prescott</i></p> <p>11 Peptide Antibiotics: Polymyxins, Glycopeptides, Bacitracin, and Fosfomycin 189<br /><i>Patricia M. Dowling</i></p> <p>12 Lincosamides, Pleuromutilins, and Streptogramins 199<br /><i>Steeve Giguère</i></p> <p>13 Macrolides, Azalides, and Ketolides 211<br /><i>Steeve Giguère</i></p> <p>14 Aminoglycosides and Aminocyclitols 233<br /><i>Patricia M. Dowling</i></p> <p>15 Tetracyclines 257<br /><i>Jérôme R.E. del Castillo</i></p> <p>16 Chloramphenicol, Thiamphenicol, and Florfenicol 269<br /><i>Patricia M. Dowling</i></p> <p>17 Sulfonamides, Diaminopyrimidines, and Their Combinations 279<br /><i>John F. Prescott</i></p> <p>18 Fluoroquinolones 295<br /><i>Steeve Giguère and Patricia M. Dowling</i></p> <p>19 Miscellaneous Antimicrobials: Ionophores, Nitrofurans, Nitroimidazoles, Rifamycins, and Others 315<br /><i>Patricia M. Dowling</i></p> <p>20 Antifungal Chemotherapy 333<br /><i>Steeve Giguère</i></p> <p><b>Section III Special Considerations_357</b></p> <p>21 Prophylactic Use of Antimicrobial Agents, and Antimicrobial Chemotherapy for the Neutropenic Patient 359<br /><i>Steeve Giguère, Anthony C.G. Abrams-Ogg, and Stephen A. Kruth</i></p> <p>22 Performance Uses of Antimicrobial Agents and Non-antimicrobial Alternatives 379<br /><i>Thomas R. Shryock and Stephen W. Page</i></p> <p>23 Antimicrobial Therapy of Selected Organ Systems 395<br /><i>Patricia M. Dowling</i></p> <p>24 Antimicrobial Therapy of Selected Bacterial Infections 421<br /><i>Steeve Giguère</i></p> <p>25 Antimicrobial Drug Residues in Foods of Animal Origin 431<br /><i>Patricia M. Dowling</i></p> <p>26 Regulation of Antimicrobial Use in Animals 443<br /><i>Karolina Törneke and Christopher Boland</i></p> <p><b>Section IV A ntimicrobial Drug Use in Selected Animal Species 455</b><br /><br />27 Antimicrobial Drug Use in Horses 457<br /><i>Steeve Giguère and Tiago Afonso</i></p> <p>28 Antimicrobial Drug Use in Dogs and Cats 473<br /><i>Jane E. Sykes</i></p> <p>29 Antimicrobial Drug Use in Cattle 495<br /><i>Michael D. Apley and Johann F. Coetzee</i></p> <p>30 Antimicrobial Drug Use in Mastitis 519<br /><i>Sarah Wagner and Ron Erskine</i></p> <p>31 Antimicrobial Drug Use in Sheep and Goats 529<br /><i>Chris R. Clark</i></p> <p>32 Antimicrobial Drug Use in New World Camelids 541<br /><i>Christopher K. Cebra and Margaret L. Cebra</i></p> <p>33 Antimicrobial Drug Use in Swine 553<br /><i>David G.S. Burch</i></p> <p>34 Antimicrobial Drug Use in Poultry 569<br /><i>Charles L. Hofacre, Jenny A. Fricke, and Tom Inglis</i></p> <p>35 Antimicrobial Drug Use in Companion Birds 589<br /><i>Keven Flammer</i></p> <p>36 Antimicrobial Drug Use in Rabbits, Rodents, and Ferrets 601<br /><i>Colette L. Wheler</i></p> <p>37 Antimicrobial Drug Use in Reptiles 623<br /><i>Ramiro Isaza and Elliott R. Jacobson</i></p> <p>38 Antimicrobial Drug Use in Zoological Animals 637<br /><i>Ellen Wiedner and Robert P. Hunter</i></p> <p>39 Antimicrobial Drug Use in Aquaculture 645<br /><i>Renate Reimschuessel, Ron A. Miller, and Charles M. Gieseker</i></p> <p>Index 663</p>

<p>“Overall, this book provides an excellent resource for the whole topic of veterinary prescribing of antibacterial and antifungal drugs from both a veterinary clinical and a public health viewpoint.”  (<i>Veterinary</i> <i>Record</i><i>, 31 May 2014)</i></p> <p>“The result is a solid textbook highly recommended for any veterinary reference library.”<i>  (Midwest Book Review</i>, 1 March 2014)</p>

<p><b>THE EDITORS</b> <p><b>Steeve Giguère</b>, DVM, PhD, DACVIM, is Professor of Large Animal Internal Medicine and the Marguerite Hodgson Chair in Equine Studies at the College of Veterinary Medicine, University of Georgia, in Athens, Georgia. <p><b>John F. Prescott,</b> MA, VetMB, PhD, is Professor in the Department of Pathobiology at the University of Guelph in Guelph, Ontario. <p><b>Patricia M. Dowling</b>, DVM, MS, DACVIM, DACVCP, is Professor of Veterinary Clinical Pharmacology at the University of Saskatchewan in Saskatoon, Saskatchewan.

<p><b>ANTIMICROBIAL THERAPY<br> IN VETERINARY MEDICINE</b> <p><b>FIFTH EDITION</b> <p>The fifth edition of <i>Antimicrobial Therapy in Veterinary Medicine</i>, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, <i>Antimicrobial Therapy in Veterinary Medicine</i> offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy. <p>Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. <i>Antimicrobial Therapy in Veterinary Medicine</i> is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists. <p><b>KEY FEATURES</b> <ul> <li>Presents a comprehensive reference on veterinary applications for antimicrobial drugs, written by leaders in the field</li> <li>Provides a fully up-to-date, current resource on antimicrobial therapy, with updates throughout the book</li> <li>Features a new chapter on antimicrobial therapy in zoological species</li> <li>Covers common infectious diseases and appropriate dosages for frequently used antimicrobial agents in many species</li> <li>Offers tables, diagrams, and photos to supplement the text</li> </ul> <p><b>RELATED TITLES</b> <p><b><i>Guide to Antimicrobial Use in Animals</i></b> Edited by Luca Guardabassi, Lars Bogø Jensen, and Hilde Kruse 9781405150798 <p><b><i>Veterinary Pharmacology and Therapeutics, Ninth Edition</i></b> Edited by Jim E. Riviere and Mark G. Papich 9780813820613

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