Details

Introduction.- Palladium Catalyzed Oxidative Cross-Coupling Reactions.- Copper Catalyzed Oxidative Cross-Coupling Reactions.- Iron Catalyzed Oxidative Cross-Coupling Reactions.- Oxidative Cross-Coupling Reactions Catalyzed by Other Metals and Transition-Metal-Free Oxidative Coupling Reactions.

Dr. Aiwen Lei has been a Professor at the College of Chemistry & Molecular Sciences, Wuhan University, China, since 2005. He received his Ph.D. from Shanghai Institute of Organic Chemistry, Chinese Academy of Science in 2000. He was a Postdoctoral Fellow at the Department of Chemistry, the Pennsylvania State University, USA (2000-2003) and a Research Associate at the Department of Chemistry, Stanford University, USA (2003-2005). His research interests include: 1) development of highly selective and efficient transition-metal-catalyzed C-C and C-heteroatom bond formation in syntheses (e.g. oxidative coupling reactions, C-H bond functionalization); 2) small molecule (such as CO, O2, N2O, H2O2, NH3, ClO2-, etc.) activation with an emphasis on applying such molecules in efficient synthetic methods; 3) mechanistic studies including kinetic and active intermediate studies. Dr. Lei has published more than 110 peer-reviewed papers and 3 book chapters. The honors he has received include: CCS-RSC Young Chemist Award (2013), Asian Rising Stars (2013), Hubei Province Youth Medal (2013), First Class Prize of Hubei Province Natural Science Award (2012), Eli Lilly Scientific Excellence Award in Chemistry (2011), Lectureship Award under the New Phase Asian Core Program on Cutting-Edge Organic Chemistry in Asia (2011), National Science Fund for Distinguished Young Scholars (2010), CAPA Distinguished Faculty Award (2009), and etc.

This book is a comprehensive text covering the research and development trends in the booming field of transition metal catalyzed oxidative cross-coupling reactions. Oxidative cross-coupling reaction is a new method to forming chemical bonds besides the traditional cross-coupling reactions. This book provides the answers to how this coupling reaction occurs and what its advantages are. The palladium, copper and iron catalyzed oxidative cross-coupling reactions as the main focuses of interest are described in detail. The oxidative cross-coupling reactions catalyzed by other metals and transition-metal-free oxidative coupling reactions are also introduced.This book provides a useful reference source for researchers and graduates in the field of transition metal catalyzed coupling reactions. It is also valuable to researchers working in pharmaceutical companies, fine organic chemical companies, and etc.

Describes a new type of cross-coupling reaction: oxidative cross-coupling reaction Discusses in detail the functions of different transition metal catalysts in oxidative cross-coupling reaction Illustrates both the reactions and the mechanisms Includes the C-C bond formation by the cleavage of two C-H bonds With more than 300 illustrations